le jeudi 02 septembre 2021
Les chercheurs de l’IPNP ont besoin de vos dons pour développer et mettre en place les projets de recherche. Pour connaître nos équipes et obtenir le bulletin de soutien, merci de cliquer sur Lire la suite...
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le jeudi 08 avril 2021
The IPNP wants to welcome new members to our iSAB and thank our outgoing members, as well as congratulates Prof. Volker Haucke who is the new president of iSAB for the period 2021-2025. It’s an honor to welcome Profs. Rohini Kuner and Carol Tamminga, who join the other esteemed members of our Board. We are grateful and excited to have this group of individuals join the board and bring their unique talents, expertise and perspectives to the work of the IPNP in order to further understanding...
Lire la suitele jeudi 03 juin 2021
Pavel Lindberg, chargé de recherche Inserm à l’Institut de Psychiatrie et de Neurosciences de Paris (unité Inserm 1266 / Université de Paris, IPNP), est l’un des co-fondateurs de Dextrain, une start-up qui propose des technologies d’évaluation et de rééducation de la dextérité manuelle chez les patients victimes d’accidents vasculaires cérébraux (AVC). Les brevets et logiciels utilisés de Dextrain sont directement issus des technologies conduites au sein de l’IPNP. Améliorer...
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le lundi 14 juin 2021
MICAL-L1 is required for cargo protein delivery to the cell surface. Sikora R, Bun P, Danglot L, Alqabandi M, Bassereau P, Niedergang F, Galli T, Zahraoui A.Biol Open. 2021 Jun 15;10(6). doi: 10.1242/bio.058008. Epub 2021 Jun 8. PubMed PMID: 34100897. Download from HAL-INSERM Secreted proteins are transported along intracellular route from the endoplasmic reticulum through the Golgi before reaching the plasma membrane. Small GTPase Rab and their effectors play a key role in membrane...
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le jeudi 03 juin 2021
Association between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: an observational multicenter study. Hoertel N, Sánchez-Rico M, Gulbins E, Kornhuber J, Carpinteiro A, Lenze EJ, Reiersen AM, Abellán M, De La Muela P, Vernet R, Blanco C, Cougoule C, Beeker N, Neuraz A, Gorwood P, Alvarado JM, Meneton P, Limosin F. Clin Pharmacol Ther. 2021 May 29;. doi: 10.1002/cpt.2317. [Epub ahead of print] PubMed PMID: 34050932. Download from HAL-INSERM Several...
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le mercredi 02 juin 2021
The multiple facets of Cajal-Retzius neurons. Causeret F, Moreau MX, Pierani A, Blanquie O. Development. 2021 Jun 1;148(11). doi: 10.1242/dev.199409. Epub 2021 May 28. PubMed PMID: 34047341. Download from HAL-INSERM Cajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs lies in the fact they are initially embedded into the immature neuronal network before being almost completely eliminated...
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le jeudi 27 mai 2021
Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1. Robert V, Therreau L, Chevaleyre V, Lepicard E, Viollet C, Cognet J, Huang AJ, Boehringer R, Polygalov D, McHugh TJ, Piskorowski RA. Elife. 2021 May 18;10. doi: 10.7554/eLife.63352. PubMed PMID: 34003113. Download from HAL-INSERM The hippocampus is critical for memory formation. The hypothalamic supramammillary nucleus (SuM) sends long-range projections to hippocampal area CA2. While the...
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le mercredi 19 mai 2021
Non-cell-autonomous OTX2 transcription factor regulates anxiety-related behavior in the mouse. Vincent C, Gilabert-Juan J, Gibel-Russo R, Alvarez-Fischer D, Krebs MO, Le Pen G, Prochiantz A, Di Nardo AA. Mol Psychiatry. 2021 May 7;. doi: 10.1038/s41380-021-01132-y. [Epub ahead of print] PubMed PMID: 33963285. Download from HAL-INSERM The OTX2 homeoprotein transcription factor is expressed in the dopaminergic neurons of the ventral tegmental area, which projects to limbic structures controlling...
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le lundi 17 mai 2021
Okur-Chung neurodevelopmental syndrome-linked CK2α variants have reduced kinase activity. Dominguez I, Cruz-Gamero JM, Corasolla V, Dacher N, Rangasamy S, Urbani A, Narayanan V, Rebholz H. Hum Genet. 2021 May 4;. doi: 10.1007/s00439-021-02280-5. [Epub ahead of print] PubMed PMID: 33944995. The Okur-Chung neurodevelopmental syndrome, or OCNDS, is a newly discovered rare neurodevelopmental disorder. It is characterized by developmental delay, intellectual disability, behavioral problems (hyperactivity,...
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le lundi 17 mai 2021
Impact of Intensive Gait Training With and Without Electromechanical Assistance in the Chronic Phase After Stroke-A Multi-Arm Randomized Controlled Trial With a 6 and 12 Months Follow Up. Palmcrantz S, Wall A, Vreede KS, Lindberg P, Danielsson A, Sunnerhagen KS, Häger CK, Borg J. Front Neurosci. 2021;15:660726. doi: 10.3389/fnins.2021.660726. eCollection 2021. PubMed PMID: 33967683; PubMed Central PMCID: PMC8100236. Download from HAL-INSERM Introduction: Movement related impairments and...
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le lundi 03 mai 2021
Case Report: Cerebrovascular Events Associated With Bacterial and SARS-CoV-2 Infections in an Adolescent. de Marcellus C, Dupic L, Roux CJ, El Aouane El Ghomari I, Parize P, Luscan R, Moulin F, Kossorotoff M. Front Neurol. 2021 Apr 8;12:606617. doi: 10.3389/fneur.2021.606617. eCollection 2021. PubMed PMID: 33897582 Neurologic manifestations associated with Covid-19 are increasingly reported, especially stroke and acute cerebrovascular events. Beyond cardiovascular risk factors associated...
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le lundi 26 avril 2021
Specific contribution of neurons from the Dbx1 lineage to the piriform cortex. Shabangu T, Chen HL, Zhuang ZH, Pierani A, Chen CF, Chou SJ. Sci Rep. 2021 Apr 16;11(1):8349. doi: 10.1038/s41598-021-86512-8. PubMed PMID: 33863910; PubMed Central PMCID: PMC8052341. The piriform cortex (PC) is a major cortical processing center for the sense of smell that receives direct inputs from the olfactory bulb. In mice, the PC consists of three neuronal layers, which are populated by cells with distinct...
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le lundi 26 avril 2021
Cathodal Transcranial Direct Current Stimulation in Acute Ischemic Stroke: Pilot Randomized Controlled Trial. Pruvost-Robieux E, Benzakoun J, Turc G, Marchi A, Mancusi RL, Lamy C, Domigo V, Oppenheim C, Calvet D, Baron JC, Mas JL, Gavaret M. Stroke. 2021 Apr 19;:STROKEAHA120032056. doi: 10.1161/STROKEAHA.120.032056. [Epub ahead of print] PubMed PMID: 33866820. In acute stroke, preventing infarct growth until complete recanalization occurs is a promising approach as an adjunct to reperfusion...
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