le mardi 08 décembre 2020


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Les chercheurs de l’IPNP ont besoin de vos dons pour développer et mettre en place les projets de recherche. Pour connaître nos équipes et obtenir le bulletin de soutien, merci de cliquer sur Lire la suite...

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le vendredi 04 décembre 2020


Crosstalk between morphogenesis and cell fate in epithelia


  Version pdf Lien Zoom : https://u-paris.zoom.us/j/84585983874?pwd=TisrSlhWcWFLQ2ZVMjMxaENCbjNHQT09...

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le jeudi 29 octobre 2020


In Memoriam Dr Deborah L. Levy


It is with great sadness that we share news of the passing of Deborah Levy. Since 2015, Debbie had been a member of IPNP international Scientific Advisory Board. She participated in every single evaluation during the last five years, including 3 open calls and the evaluation of our 2019-2024 plan. During this time, Debbie befriended many IPNP scientists. We benefitted not only from her intelligence and scientific insight, but also enjoyed her humor and warmth. The entire iSAB and IPNP community mourn...

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le vendredi 13 novembre 2020


Ramoz et al. Transl Psychiatry. 2020


  Corticotropin releasing hormone receptor CRHR1 gene is associated with tianeptine antidepressant response in a large sample of outpatients from real-life settings. T Ramoz N, Hoertel N, Nobile B, Voegeli G, Nasr A, Le Strat Y, Courtet P, Gorwood P.ransl Psychiatry. 2020 Nov 5;10(1):378. doi: 10.1038/s41398-020-01067-y. PMID: 33154348. Download from HAL-INSERM Polymorphisms of genes involved in the hypothalamic-pituitary-adrenocortical (HPA) axis have been associated with response to several...

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le vendredi 13 novembre 2020


Rollins et al. Transl Psychiatry. 2020


  Evidence in cortical folding patterns for prenatal predispositions to hallucinations in schizophrenia. Rollins CPE, Garrison JR, Arribas M, Seyedsalehi A, Li Z, Chan RCK, Yang J, Wang D, Liò P, Yan C, Yi ZH, Cachia A, Upthegrove R, Deakin B, Simons JS, Murray GK, Suckling J. Transl Psychiatry. 2020 Nov 6;10(1):387. doi: 10.1038/s41398-020-01075-y. PMID: 33159044. Download from HAL-INSERM All perception is a construction of the brain from sensory input. Our first perceptions begin during gestation,...

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le mercredi 28 octobre 2020


Rebholz et al. Front. Neurol 2020


Loss of Olfactory Function—Early Indicator for Covid-19, Other Viral Infections and Neurodegenerative Disorders. Rebholz H, Braun RF, Ladage D, Knoll W, Kleber C, Hassel AW.  Front. Neurol., 26 October 2020 | https://doi.org/10.3389/fneur.2020.569333 Download from HAL-INSERM   The loss of the senses of smell (anosmia) and taste (ageusia) are rather common disorders, affecting up to 20% of the adult population. Yet, this condition has not received the attention it deserves, most probably because...

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le lundi 26 octobre 2020


Pr Jean-Louis Mas, Prix Scientifique Jean-Paul Binet 2020 de la Fondation pour la Recherche Médicale


Le Prix Scientifique Jean-Paul Binet est issu d’une donation de Jean-Paul Binet. Il est destiné à récompenser des travaux de recherches cliniques ou expérimentales sur les pathologies cardiovasculaires ou sur les xénogreffes.   Lauréat : Jean-Louis Mas Professeur de Neurologie à l’Université de Paris Chef du service de Neurologie de l’hôpital Sainte-Anne, Paris Responsable de l’équipe « Accidents vasculaires cérébraux : déterminants du pronostic, recherche translationnelle,...

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le lundi 26 octobre 2020


Medvedeva & Pierani. Front. Cell Dev. Biol. 2020


How Do Electric Fields Coordinate Neuronal Migration and Maturation in the Developing Cortex? Medvedeva, V, Pierani, A. Front. Cell Dev. Biol. 2020 Sep 8: 1006.doi:10.3389/fcell.2020.580657 Download from HAL-INSERM : https://www.hal.inserm.fr/inserm-02973314   During development the vast majority of cells that will later compose the mature cerebral cortex undergo extensive migration to reach their final position. In addition to intrinsically distinct migratory behaviors, cells encounter and...

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le mardi 13 octobre 2020


Benamer et al. Nat Commun. 2020


Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits. Benamer N, Vidal M, Balia M, Angulo MC. Nat Commun 11, 5151 (2020). https://doi.org/10.1038/s41467-020-18984-7   Abstract Myelination of projection neurons by oligodendrocytes is key to optimize action potential conduction over long distances. However, a large fraction of myelin enwraps the axons of parvalbumin-positive fast-spiking interneurons (FSI), exclusively involved in local cortical circuits....

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le lundi 05 octobre 2020


Chen et al. Nature. 2020


A hypothalamic novelty signal modulates hippocampal memory.  Chen S, He L, Huang AJY, Boehringer R, Robert V, Wintzer ME, Polygalov D, Weitemier AZ, Tao Y, Gu M, Middleton SJ, Namiki K, Hama H, Therreau L, Chevaleyre V, Hioki H, Miyawaki A, Piskorowski RA, McHugh TJ. Nature. 2020 Sep 30;. doi: 10.1038/s41586-020-2771-1. [Epub ahead of print] PubMed PMID: 32999460.   Abstract The ability to recognize information that is incongruous with previous experience is critical for survival. Novelty signals...

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le mercredi 23 septembre 2020


Gallo et al. J Cell Sci. 2020


  Role of the Sec22b-E-Syt complex in neurite growth and ramification. Gallo A, Danglot L, Giordano F, Hewlett B, Binz T, Vannier C, Galli T. J Cell Sci. 2020 Sep 15;133(18):jcs247148. doi: 10.1242/jcs.247148. PMID: 32843578. Download from HAL-INSERM Abstract Axons and dendrites are long and often ramified neurites that need particularly intense plasma membrane (PM) expansion during the development of the nervous system. Neurite growth depends on non-fusogenic Sec22b-Stx1 SNARE complexes at...

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le lundi 07 septembre 2020


Ferrier et al Proc Natl Acad Sci U S A. 2020


  Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain.  Ferrier J, Tiran E, Deffieux T, Tanter M, Lenkei Z. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15270-15280. doi: 10.1073/pnas.1920475117. Epub 2020 Jun 15. PubMed PMID: 32541017; PubMed Central PMCID: PMC7334502. Abstract The default mode network (DMN) has been defined in functional brain imaging studies as a set of highly connected brain areas, which are...

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New postdoctoral postition in the team Chevaleyre / Piskorowski


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POSTDOCTORAL POSITION (Team Angulo)


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