le mardi 08 décembre 2020
Les chercheurs de l’IPNP ont besoin de vos dons pour développer et mettre en place les projets de recherche. Pour connaître nos équipes et obtenir le bulletin de soutien, merci de cliquer sur Lire la suite...
Lire la suite
le jeudi 29 octobre 2020
It is with great sadness that we share news of the passing of Deborah Levy. Since 2015, Debbie had been a member of IPNP international Scientific Advisory Board. She participated in every single evaluation during the last five years, including 3 open calls and the evaluation of our 2019-2024 plan. During this time, Debbie befriended many IPNP scientists. We benefitted not only from her intelligence and scientific insight, but also enjoyed her humor and warmth. The entire iSAB and IPNP community mourn...
Lire la suite
le mercredi 13 janvier 2021
Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone. Seners P, Ben Hassen W, Lapergue B, Arquizan C, Heldner MR, Henon H, Perrin C, Strambo D, Cottier JP, Sablot D, Girard Buttaz I, Tamazyan R, Preterre C, Agius P, Laksiri N, Mechtouff L, Béjot Y, Duong DL, Mounier-Vehier F, Mione G, Rosso C, Lucas L, Papassin J, Aignatoaie A, Triquenot A, Carrera E, Niclot P, Obadia A, Lyoubi A, Garnier P, Crainic...
Lire la suite
le mardi 05 janvier 2021
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients. Santos R, Linker SB, Stern S, Mendes AP, Shokhirev MN, Erikson G, Randolph-Moore L, Racha V, Yeni K, Kelsoe JR, Bang AG, Alda M, Marchetto MC, Gage FH. Mol Psychiatry. 2021. https://doi.org/10.1038/s41380-020-00981-3. Download from HAL-INSERM Bipolar disorder (BD) is a psychiatric condition characterized by depressive and manic episodes that affect 2% of the...
Lire la suite
le mercredi 30 décembre 2020
Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth. Wojnacki J, Nola S, Bun P, Cholley B, Filippini F, Pressé MT, Lipecka J, Man Lam S, N'guyen J, Simon A, Ouslimani A, Shui G, Fader CM, Colombo MI, Guerrera IC, Galli T. Cell Rep. 2020 Dec 22;33(12):108536. doi: 10.1016/j.celrep.2020.108536. PubMed PMID: 33357422. Download from HAL-INSERM VAMP7 is involved in autophagy and in exocytosis-mediated neurite growth, two yet unconnected cellular pathways. Here, we find that...
Lire la suite
le lundi 07 décembre 2020
Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo. Mozafari S, Starost L, Manot-Saillet B, Garcia-Diaz B, Xu YKT, Roussel D, Levy MJF, Ottoboni L, Kim KP, Schöler HR, Kennedy TE, Antel JP, Martino G, Angulo MC, Kuhlmann T, Evercooren AB. Sci Adv. 2020 Dec;6(49). doi: 10.1126/sciadv.abc6983. Print 2020 Dec. PubMed PMID: 33277253. Download from HAL-INSERM: https://www.hal.inserm.fr/inserm-03043177 Remyelination failure...
Lire la suite
le lundi 07 décembre 2020
Selective activation of D1 dopamine receptors exerts antidepressant-like activity in rats. Desormeaux C, Demars F, Davenas E, Jay TM, Lavergne F. J Psychopharmacol. 2020 Dec;34(12):1443-1448. doi: 10.1177/0269881120959613. Epub 2020 Oct 8. PubMed PMID: 33256509. Download from HAL-INSERM : https://www.hal.inserm.fr/inserm-03043556 Background: Major depressive disorder is a common illness that severely decreases psychosocial functioning. Due to the major limitations of current treatments including...
Lire la suite
le vendredi 13 novembre 2020
Corticotropin releasing hormone receptor CRHR1 gene is associated with tianeptine antidepressant response in a large sample of outpatients from real-life settings. T Ramoz N, Hoertel N, Nobile B, Voegeli G, Nasr A, Le Strat Y, Courtet P, Gorwood P.ransl Psychiatry. 2020 Nov 5;10(1):378. doi: 10.1038/s41398-020-01067-y. PMID: 33154348. Download from HAL-INSERM Polymorphisms of genes involved in the hypothalamic-pituitary-adrenocortical (HPA) axis have been associated with response to several...
Lire la suite
le vendredi 13 novembre 2020
Evidence in cortical folding patterns for prenatal predispositions to hallucinations in schizophrenia. Rollins CPE, Garrison JR, Arribas M, Seyedsalehi A, Li Z, Chan RCK, Yang J, Wang D, Liò P, Yan C, Yi ZH, Cachia A, Upthegrove R, Deakin B, Simons JS, Murray GK, Suckling J. Transl Psychiatry. 2020 Nov 6;10(1):387. doi: 10.1038/s41398-020-01075-y. PMID: 33159044. Download from HAL-INSERM All perception is a construction of the brain from sensory input. Our first perceptions begin during gestation,...
Lire la suite
le mercredi 28 octobre 2020
Loss of Olfactory Function—Early Indicator for Covid-19, Other Viral Infections and Neurodegenerative Disorders. Rebholz H, Braun RF, Ladage D, Knoll W, Kleber C, Hassel AW. Front. Neurol., 26 October 2020 | https://doi.org/10.3389/fneur.2020.569333 Download from HAL-INSERM The loss of the senses of smell (anosmia) and taste (ageusia) are rather common disorders, affecting up to 20% of the adult population. Yet, this condition has not received the attention it deserves, most probably because...
Lire la suite
le lundi 26 octobre 2020
Le Prix Scientifique Jean-Paul Binet est issu d’une donation de Jean-Paul Binet. Il est destiné à récompenser des travaux de recherches cliniques ou expérimentales sur les pathologies cardiovasculaires ou sur les xénogreffes. Lauréat : Jean-Louis Mas Professeur de Neurologie à l’Université de Paris Chef du service de Neurologie de l’hôpital Sainte-Anne, Paris Responsable de l’équipe « Accidents vasculaires cérébraux : déterminants du pronostic, recherche translationnelle,...
Lire la suite