le jeudi 30 avril 2020
Les chercheurs de l’IPNP ont besoin de vos dons pour développer et mettre en place les projets de recherche. Pour connaître nos équipes et obtenir le bulletin de soutien, merci de cliquer sur Lire la suite...
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le mardi 31 mars 2020
Cachia A, Cury C, Brunelin J, Plaze M, Delmaire C, Oppenheim C, Medjkane F, Thomas P, Jardri R. Deviations in early hippocampus development contribute to visual hallucinations in schizophrenia. Transl Psychiatry. 2020 Mar 25;10(1):102. doi: 10.1038/s41398-020-0779-9. PubMed PMID: 32214096; PubMed Central PMCID: PMC7096500. Auditory hallucinations (AHs) are certainly the most emblematic experiences in schizophrenia, but visual hallucinations (VHs) are also commonly observed in this developmental...
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le jeudi 26 mars 2020
Ratelade J, Klug NR, Lombardi D, Angelim MKSC, Dabertrand F, Domenga-Denier V, Al-Shahi Salman R, Smith C, Gerbeau JF, Nelson MT, Joutel A. Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage. Circulation. 2020 Mar 18;. doi: 10.1161/CIRCULATIONAHA.119.040963. [Epub ahead of print] PubMed PMID: 32183562. Download from HAL-INSERM Background: Spontaneous deep intracerebral hemorrhage (ICH) is a devastating...
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le jeudi 20 février 2020
Tripathi A, Spedding M, Schenker E, Didriksen M, Cressant A, Jay TM. Cognition- and circuit-based dysfunction in a mouse model of 22q11.2 microdeletion syndrome: effects of stress. Transl Psychiatry. 2020 Jan 28;10(1):41. doi: 10.1038/s41398-020-0687-z. PubMed PMID: 32066701. Genetic microdeletion at the 22q11 locus is associated with very high risk for schizophrenia. The 22q11.2 microdeletion (Df(h22q11)/+) mouse model shows cognitive deficits observed in this disorder, some of which can be linked...
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le vendredi 14 février 2020
Nocera S, Simon A, Fiquet O, Chen Y, Gascuel J, Datiche F, Schneider N, Epelbaum J, Viollet C. Somatostatin Serves a Modulatory Role in the Mouse Olfactory Bulb: Neuroanatomical and Behavioral Evidence. Front Behav Neurosci. 2019;13:61. doi: 10.3389/fnbeh.2019.00061. eCollection 2019. PubMed PMID: 31024270; PubMed Central PMCID: PMC6465642. Somatostatin (SOM) and somatostatin receptors (SSTR1-4) are present in all olfactory structures, including the olfactory bulb (OB), where SOM modulates physiological...
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le vendredi 14 février 2020
Schneider NY, Chaudy S, Epstein AL, Viollet C, Benani A, Pénicaud L, Grosmaître X, Datiche F, Gascuel J. Centrifugal projections to the main olfactory bulb revealed by trans-synaptic retrograde tracing in mice. J Comp Neurol. 2019 Dec 23;. doi: 10.1002/cne.24846. [Epub ahead of print] PubMed PMID: 31872441.. A wide range of evidence indicates that olfactory perception is strongly involved in food intake. However, the polysynaptic circuitry linking the brain areas involved in feeding behavior...
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le jeudi 13 février 2020
Benamer N, Vidal M, Angulo MC. The cerebral cortex is a substrate of multiple interactions between GABAergic interneurons and oligodendrocyte lineage cells. Neurosci Lett. 2020 Jan 10;715:134615. doi: 10.1016/j.neulet.2019.134615. Epub 2019 Nov 9. Review. PubMed PMID: 31711979. In the cerebral cortex, GABAergic interneurons and oligodendrocyte lineage cells share different characteristics and interact despite being neurons and glial cells, respectively. These two distinct...
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le jeudi 13 février 2020
Riva M*, Genescu I*, Habermacher C*, Orduz D, Ledonne F, Rijli FM, López-Bendito G, Coppola E, Garel S#, Angulo MC#, Pierani A#. Activity-dependent death of transient Cajal-Retzius neurons is required for functional cortical wiring. Elife. 2019 Dec 31;8. pii: e50503. doi: 10.7554/eLife.50503. PubMed PMID: 31891351. *Co-first authors; #Co-last authors Programmed cell death and early activity contribute to the emergence of functional cortical circuits. While most neuronal populations are scaled-down...
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