le Friday 30 April 2021
Les chercheurs de l’IPNP ont besoin de vos dons pour développer et mettre en place les projets de recherche. Pour connaître nos équipes et obtenir le bulletin de soutien, merci de cliquer sur Lire la suite...
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le Thursday 08 April 2021
The IPNP wants to welcome new members to our iSAB and thank our outgoing members, as well as congratulates Prof. Volker Haucke who is the new president of iSAB for the period 2021-2025. It’s an honor to welcome Profs. Rohini Kuner and Carol Tamminga, who join the other esteemed members of our Board. We are grateful and excited to have this group of individuals join the board and bring their unique talents, expertise and perspectives to the work of the IPNP in order to further understanding...
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le Monday 12 April 2021
À l'hôpital Sainte-Anne de Paris, une équipe Inserm, essentiellement constituée de médecin-chercheurs, mène de front soins aux patients et projets de recherche clinique consacrés à la prévention, à la phase aiguë et à la rééducation des accidents vasculaires cérébraux (AVC). Adapté de Vignette de l’article : © Julie Bourges. INSERM Lire la suite...
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le Tuesday 16 March 2021
Contenu : Physical exercise-related endophenotypes in anorexia nervosa. Di Lodovico L, Hatteea H, Couton C, Duriez P, Treasure J, Gorwood P. Int J Eat Disord. 2021 Mar 12;. doi: 10.1002/eat.23503. [Epub ahead of print] PubMed PMID: 33710637. Download from HAL-INSERM Background: The persistence of physical exercise in anorexia nervosa (AN) despite underweight and its maintaining factors are poorly understood. The aim of this study was to explore the attitudes toward physical exercise and...
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le Tuesday 09 March 2021
Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes. Vadodaria KC, Mendes APD, Mei A, Racha V, Erikson G, Shokhirev MN, Oefner R, Heard KJ, McCarthy MJ, Eyler L, Kelsoe JR, Santos R, Marchetto MC, Gage FH. Stem Cell Reports. 2021 Feb 23;. doi: 10.1016/j.stemcr.2021.02.004. [Epub ahead of print] PubMed PMID: 33667413. Download from HAL-INSERM This article has been chosen for a Press Release by Cell Press in the AAAS platform EurekAlert. The article...
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le Thursday 25 February 2021
Can Enhancing Neuronal Activity Improve Myelin Repair in Multiple Sclerosis? Maas DA, Angulo MC. Front. Cell. Neurosci., 23 February 2021. doi: 10.3389/fncel.2021.645240. Download from HAL-INSERM Enhanced neuronal activity in the healthy brain can induce de novo myelination and behavioral changes. As neuronal activity can be achieved using non-invasive measures, it may be of interest to utilize the innate ability of neuronal activity to instruct myelination as a novel strategy for myelin...
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le Wednesday 17 February 2021
One year after the COVID-19: what have we learnt, what shall we do next?. Gorwood P, Fiorillo A. Eur Psychiatry. 2021 Feb 15; 1-5. doi: 10.1192/j.eurpsy.2021.9. [Epub ahead of print] PubMed PMID: 33583453. Download from HAL-INSERM We are still within the acute phase of the COVID-19 pandemic, so getting lessons of how we coped with it during its first year of life is of interest. The European Psychiatric Association (EPA) has been trying to help patients, caregivers and policy makers to concentrate...
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le Wednesday 17 February 2021
ER-PM Contact Sites – SNARING Actors in Emerging Functions. Hewlett B, Pratap Singh N, Vannier C, Galli T. Front. Cell Dev. Biol., 11 February 2021. https://doi.org/10.3389/fcell.2021.635518 Download from HAL-INSERM Review Article The compartmentalisation achieved by confining cytoplasm into membrane-enclosed organelles in eukaryotic cells is essential for maintaining vital functions including ATP production, synthetic and degradative pathways. While intracellular organelles are highly specialised...
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le Friday 12 February 2021
Introducing secretory reticulophagy/ER-phagy (SERP), a VAMP7-dependent pathway involved in neurite growth. Vats S, Galli T. Autophagy. 2021 Feb 8;:1-3. doi: 10.1080/15548627.2021.1883886. [Epub ahead of print] PubMed PMID: 33554711. Download from HAL-INSERM Together with the proteasome, macroautophagy is a main pathway for the degradation of intracellular elements. Endoplasmic reticulum (ER)-autophagy i.e. reticulophagy/ER-phagy leads to the...
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le Friday 05 February 2021
Press Release: Renata Santos, Researcher at the Institut de Psychiatrie et Neurosciences de Paris (IPNP) FORBES Editors' Pick|Jan 26, 2021,12:22pm EST|1 920 views The Standard Treatment For Bipolar Disorder Doesn’t Work For Everyone, And Now Scientists Might Know Why Jackie Rocheleau, Contributor Lithium is often the first treatment option for bipolar disorder. But it’s only effective for about a third of people with the disorder. Scientists may have a clue as to why and discovered...
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le Monday 01 February 2021
Impact of the timing and adherence to face mask use on the course of the COVID-19 epidemic in France. Hoertel N, Blachier M, Sánchez-Rico M, Limosin F, Leleu H. J Travel Med. 2021 Jan 28;. doi: 10.1093/jtm/taab016. [Epub ahead of print] PubMed PMID: 33506243. Download from HAL-INSERM In this report, we sought to examine whether an early implementation of face mask use with an achievable adherence of 80% in the population would have reduced cumulative COVID-19 incidence, mortality, and...
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le Thursday 28 January 2021
Nascent fusion pore opening monitored at single-SNAREpin resolution. Heo P, Coleman J, Fleury JB, Rothman JE, Pincet F. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5). doi: 10.1073/pnas.2024922118. PubMed PMID: 33495324. Download from HAL-INSERM Significance Using our recently designed microfluidic setup, we investigated the early stage of SNAREpin-induced fusion. We discovered the existence of subsecond transient fusion pores with a well-defined subnanometer size that occur when one or...
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